Stem Cells
Overview
Stem cell research in the context of Amyotrophic Lateral Sclerosis (ALS) holds great promise for understanding the disease mechanisms and exploring potential therapeutic interventions.
Stem cells, with their unique ability to differentiate into various cell types, serve as a valuable tool for researchers studying ALS. Induced pluripotent stem cells (iPSCs) can be generated from patients' skin or blood cells, providing a platform to model ALS in the laboratory.
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National Institute of Neurological Disorders and Stroke: ALS
Sources
Du, H., Huo, Z., Chen, Y., Zhao, Z., Meng, F., Wang, X., Liu, S., Zhang, H., Zhou, F., Liu, J., Zhang, L., Zhou, S., Guan, Y., & Wang, X. (2023). Induced Pluripotent Stem Cells and Their Applications in Amyotrophic Lateral Sclerosis. Cells, 12(6), 971. https://doi.org/10.3390/cells12060971
Vasques JF, Teixeira Pinheiro LC, de Jesus Gonçalves RG, et al. Cell-based Research and Therapy for Amyotrophic Lateral Sclerosis: Promises and Challenges. In: Araki T, editor. Amyotrophic Lateral Sclerosis [Internet]. Brisbane (AU): Exon Publications; 2021 Jul 25. Chapter 7. Available from: https://www.ncbi.nlm.nih.gov/books/NBK573430/